Research

Previous Poster Presentations

A concise chemoenzymatic synthetic route to natural gangliosides and ganglioside analogs for cancer immunotherapy. P. Zhang, C.-C. Ling, S. Jacques, R. B. Zheng, and D. R. Bundle, 23rd International Carbohydrate Symposium; Whistler, British Columbia, July 23 - 28, 2006.

Chemical mapping of Trichinella spiralis antibody binding site and STD NMR studies L. Cui, C.-C. Ling, D. R. Bundle, 23rd International Carbohydrate Symposium; Whistler, British Columbia, July 23 - 28, 2006.

Diastereoselective synthesis of phytosphingosine and preparation of thioanalogs of galactosylceramide. C.-C. Ling, Y. Cai, P. Zhang, and D. R. Bundle, 23rd International Carbohydrate Symposium; Whistler, British Columbia, July 23 - 28, 2006.

Synthesis of ganglioside epitopes for oligosaccharide specific immunoadsorption therapy of Guillian-Barré syndrome. B. Kranke, P. Zhang, C.-C. Ling and D. R. Bundle, 23rd International Carbohydrate Symposium; Whistler, British Columbia, July 23 - 28, 2006.

Furanosyl oxazoline of D-GlcNAc functionalized at O-3: large-scale synthesis of ?-glycosides of unusual aminosugars. Y. Cai, C.-C. Ling and D. R. Bundle, AICCS Annual Meeting; Edmonton, Alberta; June 8-9, 2005.

Efficient synthesis of N-acetylmuramic acid and muramyl oligopeptide immuno-adjuvants. Y. Cai, C.-C. Ling, and David R. Bundle, AICCS Annual Meeting; Edmonton, Alberta; June 8-9, 2005.

A facile route to unprotected b-glycopyranosides of N-acetylglucosamine via a furanosyl oxazoline derivative. Y. Cai, C.-C. Ling and D. R. Bundle, 88th Canadian Chemistry Conference and Exhibition; Saskatoon, Saskatchewan; May 28-June 1, 2005.

An iterative approach to high affinity carbohydrate ligand design. L. Cui, C.-C. Ling and D. R. Bundle, 88th Canadian Chemistry Conference and Exhibition; Saskatoon, Saskatchewan; May 28-June 1, 2005.

A novel synthesis of phytosphingosines from 6-iodo aminosugars using a Zinc-mediated reductive elimination and olefin metathesis. Y. Cai, C.-C. Ling and D. R. Bundle, AICCS Annual Meeting and Symposium on Carbohydrate Science; Lake Louise, Alberta; April 28-30, 2005.

Synthesis of thio-analog of KRN7000. C.-C. Ling, P. Zhang and D. R. Bundle, AICCS Annual Meeting and Symposium on Carbohydrate Science; Lake Louise, Alberta; April 28-30, 2005.

Synthesis of ganglioside epitopes for oligosaccharide specific immunoadsorption therapy of Guillain-Barré syndrome. P. Zhang, C.-C. Ling, K. Townson, H. J. Willison and D. R. Bundle, AICCS Annual Meeting and Symposium on Carbohydrate Science; Lake Louise, Alberta; April 28-30, 2005.

Unique helical solution conformation in Candida albicans b(1-2)-mannopyranan oligomers. A. Otter, M. Nitz, C.-C. Ling and D. R. Bundle, 43rd ENC Conference; Santa Fe, April 2002.

Efficient synthesis of N-acetylmuramic acid and muramyl oligopeptide immuno-adjuvants. Y. Cai, C.-C. Ling, and David R. Bundle, AICCS Annual Meeting; Edmonton, Alberta; June 8-9, 2005.

A facile route to unprotected b-glycopyranosides of N-acetylglucosamine via a furanosyl oxazoline derivative. Y. Cai, C.-C. Ling and D. R. Bundle, 88th Canadian Chemistry Conference and Exhibition; Saskatoon, Saskatchewan; May 28-June 1, 2005.

An iterative approach to high affinity carbohydrate ligand design. L. Cui, C.-C. Ling and D. R. Bundle, 88th Canadian Chemistry Conference and Exhibition; Saskatoon, Saskatchewan; May 28-June 1, 2005.

A novel synthesis of phytosphingosines from 6-iodo aminosugars using a Zinc-mediated reductive elimination and olefin metathesis. Y. Cai, C.-C. Ling and D. R. Bundle, AICCS Annual Meeting and Symposium on Carbohydrate Science; Lake Louise, Alberta; April 28-30, 2005.

Synthesis of thio-analog of KRN7000. C.-C. Ling, P. Zhang and D. R. Bundle, AICCS Annual Meeting and Symposium on Carbohydrate Science; Lake Louise, Alberta; April 28-30, 2005.

Synthesis of ganglioside epitopes for oligosaccharide specific immunoadsorption therapy of Guillain-Barré syndrome. P. Zhang, C.-C. Ling, K. Townson, H. J. Willison and D. R. Bundle, AICCS Annual Meeting and Symposium on Carbohydrate Science; Lake Louise, Alberta; April 28-30, 2005.

Understanding neuropathy pathogenesis: synthesis of ganglioside BSA glycoconjugates and immobilization on sepharose gel. S. M. Andersen, C.-C. Ling, P. Zhang, K. Townson, J. Veitch, H. J. Willison and D. R. Bundle, Eurocarb Symposium 2003; Grenoble, France; 2003.

Large scale synthesis of an analog of azidosphingosine and preparation of the corresponding GM2 analog. C.-C. Ling, P. Zhang, C. M. Nycholat and D. R. Bundle, Alberta Ingenuity Centre for Carbohydrate Science - Annual Meeting; Edmonton, Alberta; 2003.

An efficient route to sphinganine, phytosphingosine and their analogs. Y. Cai, C.-C. Ling and D. R. Bundle, Banff Symposium on Organic Chemistry; Banff, Alberta; 2003.

Synthetic studies toward Lewis Y glycoconjugates. L. Liu, C.-C. Ling and D. R. Bundle, Canadian Society for Chemistry Conference and Exhibition; Vancouver, B.C., Canada; June 1-5, 2002

Candida albicans b(1-2)-mannans: unique solution conformation and the immune response to their glycoconjugates. M. Nitz, C.-C. Ling, A. Otter, J. Sadowska and D. R. Bundle, International Carbohydrate Symposium; Cairns, Australia; August 7-12, 2002.

Thio-linked oligosaccharides: better immunogens? synthesis and binding studies of S-linked trisaccharides related to shigella flexneri variant Y LPS antigens. H. N. Yu, C.-C. Ling and D. R. Bundle, Canadian Society for Chemistry Conference and Exhibition; Vancouver, B.C., Canada; June 1-5, 2002.

Determination of the binding affinity of mAb B3 for synthetic derivatives of Lewis Y using FAC/MS. L. Liu, C.-C. Ling and D. R. Bundle, Gordon Research Conference; Tilton, NH, 2001.

Construction of 1-thio-b-mannopyranosyl and 1-thio-b-rhamnopyranosyl linkages via a facile SN2 reaction. H. N. Yu, C.-C. Ling and D. R. Bundle, Gordon Research Conference; Tilton, NH; 2001.

Conformational analysis of a tethered disaccharide trapped in the anti-conformation. S. A. Wachowich-Sgarbi, C.-C. Ling, D. R. Bundle and A. Otter, Experimental NMR Conference 2000; Asilomar, California; April 9-14,